Endocrine Abstracts

Background and aim: Gestational Diabetes Mellitus (GDM) is the commonest medical pregnancy complication. Nutritional interventions come to the fore as one of the few levers for managing GDM, as many medications are either harmful to the growing fetus, or their toxicity is uncertain. The aim of this study was to assess the potential clinical features and nutritional risk factors of insulin treatment during GDM.Methods: This was a prospective study includ...

Introduction: Hyperuricemia is associated with increased cardiovascular mortality and morbidity hence the interest in screening for hyperuricemia in the type 2 diabetic population.Objective: To investigate the association between hyperuricemia and degenerative complications in type 2 diabetics.Patients and Methods: This is a retrospective study including 130 patients followed in the C department of the National Institute of Nutriti...

Introduction: Gestational diabetes mellitus (GDM) complicates approximately 3% to 9% of pregnancies. Diagnosis and treatment of GDM remain essential to limit maternal and neonatal outcomes. The aim of the study was to evaluate the difference in pregnancy outcomes between insulin- and diet-treated tunisian women with gestational diabetes.Methods: It was a prospective longitudinal study including 220 patients followed for GDM at the research unit of the C ...

Introduction: Early spontaneous miscarriage is common in diabetic women and has an unknown mechanism. This rate of spontaneous miscarriage is directly correlated to the glycemic control at the beginning of pregnancy.Objective: To assess the frequency of spontaneous miscarriage in women with diabetes.Patients and Method: This is a retrospective study including 50 diabetic women followed at department C of the National Institute of N...

Introduction: Type 1 diabetes (T1DM) is an autoimmune disease in 90% of cases and is frequently accompanied by other autoimmune diseases.Objective: To assess the frequency of autoimmune diseases in type 1 diabetics and study the particularities of this association.Patients and Method: This is a retrospective study including 120 type 1 diabetic patients hospitalized in department C of the National Institute of Nutrition in Tunis.</p...

Introduction: Dyslipidemia in type 1 diabetic patients is a frequent situation and seems to be a risk factor for the occurrence of degenerative complications. The aim of this study is to evaluate the lipid profile of type 1 diabetic patients and to study the relationship between dyslipedmia and the occurrence of degenerative complications.Method: This is a retrospective study conducted at the National Nutrition Institute of Tunis including 110 diabetic p...

Background and aim : To determine clinical and metabolic predictors of persistant abnormal glucose tolerance in post partum after gestational diabetes mellitus (GDM). Methods: This was a prospective study including 150 patients with GDM who underwent 75g oral glucose tolerance test (OGTT) at 4-12 weeks after delivery. Results: The prevalence of abnormal glucose tolerance in post partum after GDM was 32,8 % ,...

Introduction: Body mass index (BMI) and gestational weight gain are increasing globally. However, the association between gestational weight gain consistent with the Institute of Medicine (IOM) guidelines and neonatal birth weight among women with gestationnel diabetes (GDM) remain unclear.Objective: The aim of our study was to assess gestational weight gain among tunisian women with GDM and his effect on neonatal birth weight.Meth...

Introduction: Gestational diabetes mellitus (GDM) is the most common metabolic disturbance during pregnancy. The prevalence of GDM is rising and correlates with the increase in maternal obesity over recent decades. The aim of our study was to assess the association between maternal insulin resistance with pregnacy outcomes and maternal characteristics among tunisians women with GDM.Methods: A prospective longitudinal study carried out during the year 202...

Introduction: Diabetic nephropathy is a a dreadfull complication of diabetes and it is the leading cause of chronic kidney disease worldwide. Hypertension is a major cause of progression of this complication.Objective: To determine the prevalence of diabetic nephropathy, to search a correlation between the presence and duration of arterial hypertension and the occurrence of diabetic nephropathy.Patients and methods: This is a retro...